iOnco
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Pine Bark Extract / Pycnogenol

Pinus pinaster

Anti-tumourmoderate evidence

Pycnogenol (maritime pine bark extract) contains procyanidins and phenolic acids that inhibit cancer cell proliferation, reduce NF-κB signalling, and prevent metastasis. Clinical studies show Pycnogenol significantly reduces venous thromboembolism (DVT/PE) risk — the leading non-cancer cause of death in cancer patients. It also reduces retinopathy and neuropathy from treatment.

Medicinal Properties

Anti-tumourAntioxidantAnti-inflammatoryCardiovascularAnti-angiogenic
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Cancer Types Studied

BreastColonProstate

Recommended Dosage

50–200 mg standardised Pycnogenol extract daily.

Preparations

Pycnogenol Capsules

50–200 mg standardised Pycnogenol (maritime pine bark) daily. Gold-standard standardised extract with extensive human clinical data.

NIH / PubMed Research

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

  • Generally very safe — one of the most tested supplements in humans
  • May interact with immunosuppressants
  • May lower blood pressure and blood glucose
  • Avoid in autoimmune conditions without supervision

Informational only. Not medical advice. Consult your healthcare provider before use.