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Pine Bark Extract / Pycnogenol
Pinus pinaster
Anti-tumourmoderate evidence
Pycnogenol (maritime pine bark extract) contains procyanidins that inhibit cancer cell proliferation, reduce NF-κB signalling, and prevent metastasis. Clinically it significantly reduces venous thromboembolism (DVT/PE) risk — the leading non-cancer cause of death in cancer patients. It also reduces radiation-induced retinopathy and neuropathy.
Medicinal Properties
Anti-tumourAntioxidantAnti-inflammatoryCardiovascularAnti-thrombotic
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Cancer Types Studied
BreastColonProstate
Recommended Dosage
50–200 mg standardised Pycnogenol extract daily.
Preparations
Pycnogenol Capsules
50–200 mg standardised Pycnogenol (maritime pine bark) daily with food.
NIH / PubMed Research
Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.
Cautions & Interactions
- May interact with immunosuppressants
- May lower blood pressure and blood glucose
- One of the most tested supplements in humans — generally very safe
- Avoid in autoimmune conditions without supervision
Related Herbs
Informational only. Not medical advice. Consult your healthcare provider before use.