iOnco
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Wasabi

Wasabia japonica

Anti-cancermoderate evidence

Wasabi contains isothiocyanates — particularly 6-methylsulfinylhexyl isothiocyanate (6-MSITC) — that activate Nrf2 detoxification pathways, induce apoptosis in cancer cells, and inhibit metastasis. Japanese research has shown activity against colorectal, lung, and breast cancer cell lines. Wasabi isothiocyanates are more stable and bioavailable than those from horseradish or broccoli.

Medicinal Properties

Anti-cancerAnti-inflammatoryAntioxidantDetoxifyingAntimicrobial
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Cancer Types Studied

ColorectalLungBreastStomach

Recommended Dosage

Fresh wasabi root grated: 1–2 tsp daily. Wasabi extract standardised to isothiocyanates: 50–100 mg daily. Note: most commercial wasabi paste is horseradish — use genuine Wasabia japonica.

Preparations

Fresh Grated Root

Grate fresh wasabi root on a ceramic grater just before use. The volatile isothiocyanates are most potent when freshly prepared. Use 1 tsp with sushi, sashimi, or vegetable dishes.

Wasabi Extract Capsules

50–100 mg standardised extract daily. Ensure the product specifies Wasabia japonica, not horseradish (Armoracia rusticana).

NIH / PubMed Research

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

  • May irritate gastric mucosa in sensitive individuals
  • Strong blood-thinning potential at high doses — caution with anticoagulants
  • Genuine wasabi is expensive — verify product authenticity

Informational only. Not medical advice. Consult your healthcare provider before use.