Magnolia Bark / Hou Po (Honokiol)
Magnolia officinalis
Honokiol and magnolol from Magnolia bark cross the blood-brain barrier — rare for natural compounds. Honokiol induces apoptosis in breast, colon, brain, and lung cancer cells, inhibits STAT3, and shows synergy with chemotherapy. It also reduces cortisol and anxiety and has antidepressant effects — addressing the psychological burden of cancer alongside direct anti-tumour mechanisms.
Medicinal Properties
Cancer Types Studied
Recommended Dosage
200–400 mg standardised Magnolia extract (1–2% honokiol) daily.
Preparations
Magnolia Extract Capsules
200–400 mg standardised Magnolia officinalis extract daily. Often combined with Phellodendron (Relora formula) for cortisol reduction.
NIH / PubMed Research
Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.
Cautions & Interactions
- May cause sedation — avoid with other sedatives
- May potentiate anaesthetics
- Avoid in pregnancy
- Generally well-tolerated at recommended doses
Related Herbs
Informational only. Not medical advice. Consult your healthcare provider before use.