iOnco
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Chitraka / Leadwort

Plumbago zeylanica

Anti-tumourmoderate evidence

Plumbagin from Chitraka is one of the most potent natural anti-cancer naphthoquinones with documented activity against breast, colon, prostate, and ovarian cancer cells. Mechanisms include NF-κB inhibition, STAT3 blocking, and reactive oxygen species generation selective to cancer cells. Ayurveda uses Chitraka as a digestive fire-kindler and anti-tumour herb.

Medicinal Properties

Anti-tumourDigestiveAnti-inflammatoryAntimicrobialHepatoprotective
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Cancer Types Studied

BreastColonProstateOvarian

Recommended Dosage

Low doses ONLY under supervision — 125–250 mg standardised extract. Toxic at high doses.

Preparations

Ayurvedic Formula Under Supervision

Chitraka is typically used as part of classical Ayurvedic formulas (Chitrakadi Vati) under qualified supervision — NOT as a standalone high-dose supplement.

NIH / PubMed Research

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

  • TOXIC at high doses — can cause severe gastrointestinal damage and liver toxicity
  • Use ONLY under qualified Ayurvedic physician or integrative oncologist supervision
  • Do not use in pregnancy — abortifacient
  • Never self-prescribe high-dose plumbagin

Informational only. Not medical advice. Consult your healthcare provider before use.