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Chasteberry / Vitex

Vitex agnus-castus

Hormonal balancermoderate evidence

Chasteberry modulates dopamine and prolactin, reducing cyclic breast pain and normalising menstrual cycles disrupted by cancer treatment. Its diterpenes show anti-proliferative activity against breast and ovarian cancer cells. Clinical studies support its use for premenstrual symptoms and cyclical mastalgia in women undergoing cancer treatment.

Medicinal Properties

Hormonal balancerAnti-tumourAntioxidantProgesterone-modulatingAnti-inflammatory

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Cancer Types Studied

BreastOvarian

Recommended Dosage

160–400 mg standardised extract daily in the morning.

Preparations

Standardised Extract

160–400 mg Vitex agnus-castus standardised extract daily in the morning on an empty stomach.

NIH / PubMed Research

PMID 19591034Vitex agnus-castus and breast cancer — review

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

Avoid during pregnancy
May interfere with hormonal therapies — discuss with oncologist before use in hormone-sensitive cancers
May interact with dopaminergic drugs
Not recommended in oestrogen-dependent tumours without oncologist approval