iOnco
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Cayenne Pepper / Capsaicin

Capsicum annuum

Anti-tumourmoderate evidence

Capsaicin from cayenne selectively induces apoptosis in prostate, breast, colon, and pancreatic cancer cells through activation of TRPV1 receptors, while leaving normal cells unaffected. Capsaicin also provides powerful topical pain relief for neuropathic pain — a common and debilitating side effect of chemotherapy (CIPN).

Medicinal Properties

Anti-tumourAnalgesicAntioxidantAnti-inflammatoryThermogenic
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Cancer Types Studied

ProstateBreastColonPancreatic

Recommended Dosage

30–120 mg capsaicin daily in food, or capsaicin cream (0.025–0.075%) topically for pain.

Preparations

Cayenne in Food

Add generous cayenne powder to food daily — soups, curries, sauces. Start with small amounts to build tolerance.

Capsaicin Cream (Topical)

0.025–0.075% capsaicin cream applied to neuropathic pain areas 3–4x daily for CIPN pain relief. Wear gloves.

NIH / PubMed Research

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

  • Irritates mucous membranes — start low
  • Topical: burning sensation initially — wears off with regular use
  • Avoid contact with eyes and sensitive areas
  • May aggravate acid reflux in sensitive individuals

Informational only. Not medical advice. Consult your healthcare provider before use.