iOnco
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Milk Thistle

Silybum marianum

Hepatoprotectivestrong evidence

Silymarin (silibinin) is the most important herb for cancer patients on chemotherapy. It protects the liver from chemotherapy-induced toxicity, supports drug detoxification, and shows direct anti-tumour effects against prostate, breast, and colon cancers. Clinical studies confirm reduced liver enzyme elevation from chemotherapy.

Medicinal Properties

HepatoprotectiveAntioxidantAnti-tumourAnti-inflammatoryDetoxifying
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Cancer Types Studied

LiverColonBreastProstate

Recommended Dosage

420–1400 mg silymarin daily (standardised 70–80% silymarin). During chemo: 600–1200 mg daily.

Preparations

Standardised Extract Capsules

140–280 mg silymarin capsules three times daily with meals. Most effective form during chemotherapy.

Milk Thistle Tea

1 tsp ground milk thistle seeds in hot water, 10 minutes. Drink 2–3 cups daily.

NIH / PubMed Research

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

  • Very safe — well tolerated
  • May affect CYP450 metabolism of some chemo drugs — consult oncologist
  • Mild laxative in some people
  • Avoid if allergic to Asteraceae (daisy family)

Informational only. Not medical advice. Consult your healthcare provider before use.