iOnco
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Lion's Mane

Hericium erinaceus

Medicinal Mushroompreliminary evidence

Lion's Mane stimulates nerve growth factor (NGF), valuable for chemotherapy-induced peripheral neuropathy. Its polysaccharides show anti-tumour effects against gastric, colon, and leukemia cells. It also helps combat 'chemo brain' — cognitive impairment during cancer treatment.

Medicinal Properties

NeuroprotectiveImmunomodulatoryAnti-tumourNerve Growth Factor
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Cancer Types Studied

GastricColonLeukemia

Recommended Dosage

500–3000 mg Lion's Mane extract daily, standardised to >30% polysaccharides.

Preparations

Extract Capsules

500–1000 mg dual-extracted powder twice daily.

Fresh Mushroom (Cooked)

Sauté 100–200 g fresh Lion's Mane in olive oil daily. Pleasant seafood-like texture.

NIH / PubMed Research

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

  • Generally very safe
  • Avoid if allergic to mushrooms
  • Rare: allergic skin reactions
  • Digestive discomfort at very high doses

Informational only. Not medical advice. Consult your healthcare provider before use.