iOnco
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Bromelain / Pineapple Enzyme

Ananas comosus

Anti-tumourmoderate evidence

Bromelain, the proteolytic enzyme from pineapple, shows anti-cancer activity against breast, colon, lung, and ovarian cancer cells through multiple mechanisms including MAPK inhibition. It reduces cancer-associated inflammation, dissolves fibrin coats that cancer cells use to evade immune detection, enhances immune cell cytotoxicity, and reduces post-surgical swelling.

Medicinal Properties

Anti-tumourAnti-inflammatoryProteolyticImmunomodulatoryFibrinolytic
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Cancer Types Studied

BreastColonLungOvarian

Recommended Dosage

400–2000 GDU bromelain on EMPTY stomach (away from meals for anti-cancer; with meals for digestive use).

Preparations

Bromelain Capsules (Between Meals)

500–2000 mg bromelain on empty stomach between meals for anti-cancer/anti-inflammatory effects. With meals for digestion.

NIH / PubMed Research

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

  • May increase absorption of antibiotics — adjust doses if using both
  • May thin blood — caution with anticoagulants
  • Avoid before surgery
  • Pineapple allergy contraindicates use

Informational only. Not medical advice. Consult your healthcare provider before use.