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Black Pepper / Piperine

Piper nigrum

Bioavailability enhancermoderate evidence

Piperine from black pepper enhances bioavailability of curcumin by 2000% and other nutrients by 30–200%. It has direct anti-tumour activity against breast, colon, and lung cancers through apoptosis induction and stem cell suppression. Piperine is essential to take with turmeric for any therapeutic anti-cancer effect.

Medicinal Properties

Bioavailability enhancerAnti-tumourAnti-inflammatoryAntioxidantDigestive

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Cancer Types Studied

BreastColonLung

Recommended Dosage

5–20 mg piperine daily (as BioPerine supplement), or 1/4–1/2 tsp freshly ground black pepper daily in food.

Preparations

Freshly Ground Pepper in Food

Freshly grind 1/4–1/2 tsp black pepper and add to food or drinks daily. Always take with turmeric.

NIH / PubMed Research

PMID 23030611Piperine from black pepper and cancer

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

May increase absorption of medications — consult pharmacist about drug interactions
May irritate stomach lining in high amounts
Avoid during pregnancy in supplement doses
Freshly ground is far more potent than pre-ground